Skip to content

Join our newsletter

Donate to MPN-CC

Menu
MPN Cancer Connection logo
Your Future Matters
  • Understanding MPNs
    • General Information
    • An Overview of Myeloproliferative Neoplasms
    • What is Myelofibrosis?
    • What is Polycythemia Vera
    • What is Essential Thrombocythemia
  • Clinical Trials
    • Clinical Trial Finder
    • Search for Clinical Trials
    • Clinical Trial Acronyms and Abbreviations
    • Understanding the Phases of Clinical Trials
  • Our Impact
    • Donate
  • About
    • About Us
    • Our Founder
    • Our Mission
    • MPN-CC Team
    • Corporate Sponsors
  • Resources
    • Patient Resources
    • MPN Experts
    • Advocacy Partners
    • MPN Websites
    • Facebook Groups
    • Treatments
      • Ojjaara
      • Vonjo
      • BESREMi
      • Jakafi
      • INREBIC
  • Blog
    • Blog
  • Contact
Close Menu

MPN Clinical Trial Finder

Clinical Trial Finder

Clinical trials are research studies that test how well new treatments and medical approaches work in patients. Through clinical trials, doctors and researchers discover new medicines that can provide better outcomes and improve quality of life for people diagnosed with one of the chronic blood cancers, Myeloproliferative Neoplasms (MPNs).

Finding a Trial

Our MPN Clinical Trial Finder will help raise awareness and increase participation in Myeloproliferative Neoplasm clinical trials. Use the filters below to narrow the search for your specific diagnosis; Myelofibrosis (MF), Polycythemia Ver (PV), or Essential Thrombocythemia (ET). Before participating in a clinical trial, talk to your health care provider about the trials that may interest you.

The search results have been obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of participants with locations in all 50 states and 196 countries. Please refer to our terms of service below.

Filters

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.


An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.


Searching Both is inclusive of interventional and observational studies.

You can narrow your results further by searching each trial’s description for a specific word. Keep in mind that this will search the full description. We recommend carefully reviewing each trial information to ensure that it is an appropriate fit for you.

1 - 10 of 357 Trials
  • 18F-FAPI PET/MRI Imaging in Myelofibrosis: a Prospective Observational Study.

    This study intends to use a prospective, observational, self-controlled, multi-center study design to evaluate the feasibility and diagnostic efficacy of 18F-FDG PET/CT and 18F-FAPI PET/MRI imaging for the evaluation of systemic fibrosis in MF patients based on the results of bone marrow pathological biopsy, and to analyze the relationship between imaging results and clinical prognosis.

    18 Years - 80 Years
    Recruiting
    Learn More
  • 68Ga-FAPI PET/CT Imaging for Diagnosis, Grading, and Efficacy Evaluation of Myelofibrosis.

    To evaluate the diagnostic efficacy of 68Ga FAPI PET/CT in myelofibrosis and to identify fibrosis grades. To evaluate the diagnostic efficacy of 68Ga FAPIPET/CT imaging in patients with myelofibrosis, compared with conventional CT.

    18 Years and Over
    Recruiting
    Learn More
  • ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

    This research study is evaluating a drug called ABL001 taken in combination with dasatinib (Sprycel®) and prednisone (a steroid) as a possible treatment for B-cell Acute Lymphoblastic Leukemia that is BCR-ABL positive (BCR-ABL+ B-ALL) or Chronic Myeloid Leukemia (CML) in lymphoid blast crisis. BCR-ABL+ B-ALL is also called Philadelphia chromosome positive Acute Lymphoblastic Leukemia (Ph+ ALL). It is expected that 25-40 people will take part in this research study. - ABL001 - Dasatinib (Sprycel®) - Prednisone - Blinatumomab

    18 Years and Over
    Recruiting
    Learn More
  • A Clinical Trial of TQ05105 Tablets Combined With TQB3617 Capsules in the Treatment of Myelofibrosis (MF)

    This is an open, single-arm, multi-center clinical study designed to evaluate the efficacy and safety of TQ05105 Tablets combined with TQB3617 Capsules in patients with intermediate- and high-risk Myelofibrosis.

    18 Years and Over
    Recruiting
    Learn More
  • A Clinical Trial of TQ05105 Tablets Combined With TQB3909 Tablets in the Treatment of Myelofibrosis (MF)

    This is an open, single-arm, multi-center clinical study designed to evaluate the efficacy and safety of TQ05105 tablets combined with TQB3909 tablets in patients with moderate- and high-risk Myelofibrosis.

    18 Years and Over
    Recruiting
    Learn More
  • Acquired Pyruvate Kinase Deficiency In Clonal Myeloid Neoplasms

    This cross-sectional prevalence assessment study involves a single blood draw in specific patient populations to assess for enzymatic and genomic evidence for acquired pyruvate kinase deficiency.

    18 Years and Over
    Recruiting
    Learn More
  • Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants

    This clinical trial evaluates the safety and effectiveness of adding itacitinib to cyclophosphamide and tacrolimus for the prevention of graft versus host disease (GVHD) in patients undergoing hematopoietic stem cell transplant. Itacitinib is an enzyme inhibitor that may regulate the development, proliferation, and activation of immune cells important for GVHD development. Cyclophosphamide and tacrolimus are immunosuppressive agents that may prevent GVHD in patients who receive stem cell transplants. Giving itacitinib in addition to cyclophosphamide and tacrolimus may be more effective at preventing GVHD in patients receiving...

    N/A - 80 Years
    Recruiting
    Learn More
  • Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity Conditioning

    The present project aims at comparing two conditioning regimens (FM-PTCy vs FM-ATG). The hypothesis is that one or the two regimens will lead to a 2-year cGRFS rate improvement from 30% (the cGRFS rate with FM without ATG/PTCy) to 45% (Pick-a-winner phase 2 randomized study).

    18 Years - 75 Years
    Recruiting
    Learn More
  • Allogeneic Hematopoietic Cell Transplantation With Pegylated Interferon Alfa-2a for Primary and Secondary Myelofibrosis

    This is a single site, open-label, dose de-escalation, Phase 1 study of pegylated interferon alfa-2a administered after alloHCT in subjects with primary or secondary myelofibrosis. Part 1 of the study will assess the rate of dose-limiting toxicities (DLTs) during the DLT evaluation period and identify the Recommended Phase 2 Dose (RP2D). Once the RP2D is identified, 6 additional patients will be enrolled in the expansion cohort.

    18 Years and Over
    Recruiting
    Learn More
  • Allo HSCT Using RIC and PTCy for Hematological Diseases

    This is a Phase II study following subjects proceeding with our Institutional non-myeloablative cyclophosphamide/ fludarabine/total body irradiation (TBI) preparative regimen followed by a related, unrelated, or partially matched family donor stem cell infusion using post-transplant cyclophosphamide (PTCy), sirolimus and MMF GVHD prophylaxis.

    N/A - 75 Years
    Recruiting
    Learn More
← Previous 1 2 3 4 5 6 7 … 36 Next →
Powered By
The content provided on clinical trials is for informational purposes only and is not a substitute for medical consultation with your healthcare provider. We do not recommend or endorse any specific study and you are advised to discuss the information shown with your healthcare provider. While we believe the information presented on this website to be accurate at the time of writing, we do not guarantee that its contents are correct, complete, or applicable to any particular individual situation. We strongly encourage individuals to seek out appropriate medical advice and treatment from their physicians. We cannot guarantee the availability of any clinical trial listed and will not be responsible if you are considered ineligible to participate in a given clinical trial. We are also not liable for any injury arising as a result of participation.

MPN CANCER CONNECTION

is a 501 (c) (3) non-profit public charity, our tax ID number is 47-4839850.

Privacy Policy

Copyright © 2024 MPN Cancer Connection,
All Rights Reserved

Follow us on Social

RSS PV Reporter News

  • Honor those who make a difference in the myeloproliferative neoplasm community: Submit a nomination to the MPN Heroes® Recognition Program today!
  • Precision Medicine in Myeloproliferative Neoplasms (MPNs): Molecular Insights and Advances
  • What Rare Disease Day Means to Me

Recent News

  • Myelofibrosis Treatment: Optimizing JAK Inhibitor Strategies in 2024
  • MPN Research 2024: Emerging Trends

JOIN OUR NEWSLETTER

There was an error. Please try again later.

Success!

  • Sponsors
  • Impact
  • Partners
  • About
  • Contact
  • NCCN Guidelines
  • Terms
  • Privacy

Site by: Kaleidoscopic